AT10 also includes new recommendations concerning the role of aspirin for extended VTE treatment. Interestingly, the ACCP guideline gave a strong recommendation against the use of aspirin for VTE management in any patient population. In the guideline, the role of aspirin was not addressed for VTE treatment. Now, AT10 states that low-dose aspirin can be used in patients who stop anticoagulant therapy for treatment of an unprovoked proximal DVT or PE as an extended therapy grade 2B. The significant change in this recommendation stems from two recent randomized trials that compared aspirin with placebo for the prevention of VTE recurrence in patients who have completed a course of anticoagulation for a first unprovoked proximal DVT or PE.
Another significant change in AT10 is the recommendation against the routine use of compression stockings to prevent postthrombotic syndrome PTS. This change was influenced by a recent multicenter randomized trial showing that elastic compression stockings did not prevent PTS after an acute proximal DVT. Thus, for patients with acute or chronic leg pain or swelling from DVT, compression stockings may be justified. Your email address will not be published. Menu Close.
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